AtaGenix Laboratories
AtaGenix provides custom peptide synthesis services using solid-phase peptide synthesis (SPPS) for sequences up to 101 amino acids, with purity options from crude to >99%. Specialized modification capabilities include phosphorylation, methylation, acetylation, and crotonylation — directly supporting our antibody development platform for PTM-specific immunogen preparation and epitope mapping.
101 aa
Max Length
>99%
Highest Purity
~2 wks
Standard Delivery
mg–kg
Production Scale
Every peptide is delivered with HPLC purity analysis and mass spectrometry (MS) verification. Carrier protein conjugation (KLH, BSA, OVA) is available for immunization-ready antigen preparation — seamlessly connecting to our polyclonal and monoclonal antibody production pipelines.
| Service | What's Included | Timeline |
| Standard Peptide (≤30 aa) | Custom peptide + HPLC report + MS verification | ~2 weeks |
| Long Peptide (31–101 aa) | Custom peptide + HPLC + MS; may require optimization | Consult |
| Modified Peptide | Phospho / methyl / acetyl / crotonyl + HPLC + MS | Consult |
| Carrier Conjugation | Peptide + KLH / BSA / OVA conjugation for immunization | Add ~1 week |
| Gram-Scale Production | mg to kg scale; purity up to >99% | Consult |
Modification Expertise
Phosphorylation, methylation, acetylation, crotonylation, and custom chemical modifications. Essential for PTM antibody immunogen preparation — we synthesize both modified and unmodified peptides for two-round affinity purification.
Integrated with Antibody Services
Peptide synthesis + carrier conjugation + immunization + antibody production in one project. No need to coordinate between peptide vendor and antibody CRO — we handle the entire chain from epitope design to validated antibody.
Full QC Documentation
Every peptide ships with HPLC purity analysis and mass spectrometry identity confirmation. Multiple purity grades available: crude, desalted, >75%, >85%, >95%, and >99% to match your application requirements.
AtaGenix's peptide synthesis platform uses solid-phase peptide synthesis (SPPS) to produce custom peptides up to 101 amino acids in length, from milligram to kilogram scale. Purity options range from crude to >99% (HPLC-purified). Specialized modifications include phosphorylation, methylation, acetylation, and crotonylation for PTM research. Carrier protein conjugation (KLH, BSA, OVA) is available for direct use as immunogens in our polyclonal and monoclonal antibody pipelines. Standard delivery: ~2 weeks for peptides ≤30 aa. All peptides include HPLC and MS QC reports.
A standardized pipeline from sequence design to QC-verified peptide delivery. Carrier conjugation and downstream antibody production available as integrated services.
01
Sequence Design
Epitope selection
Modification site design
Solubility assessment
02
SPPS Synthesis
Solid-phase synthesis
Modification incorporation
Cleavage & deprotection
03
Purification & QC
HPLC purification
MS identity confirmation
Purity grade selection
04
Conjugation & Delivery
KLH / BSA / OVA (optional)
Lyophilized peptide
HPLC + MS reports
Service Scope
| ✓ Custom peptide synthesis up to 101 amino acids | ✓ Purity: crude, desalted, >75% to >99% |
| ✓ Phosphorylation, methylation, acetylation, crotonylation | ✓ Custom chemical modifications |
| ✓ Carrier conjugation: KLH, BSA, OVA | ✓ Milligram to kilogram scale |
| ✓ HPLC purity analysis included | ✓ MS identity verification included |
| ✓ Lyophilized delivery format | ✓ Integrated with antibody production pipeline |
| Modification | Application | Downstream Use |
| Phosphorylation | pSer, pThr, pTyr site-specific phosphorylation | Phospho-specific antibody immunogen |
| Methylation | Mono/di/tri-methylation on Lys or Arg | Histone methylation antibody immunogen |
| Acetylation | Lys acetylation at specific residues | Acetylation-specific antibody immunogen |
| Crotonylation | Lys crotonylation for epigenetic research | Crotonylation antibody immunogen |
Need antibodies from your peptide? Connect directly to our Polyclonal Antibody or Hybridoma pipeline. For PTM-specific antibodies with modified + unmodified two-round purification, see Anti-PTM Service. For epitope mapping via phage display, explore our Naïve Library Panning with peptide libraries (LiPep-7, LiPep-12).
What is the maximum peptide length you can synthesize?
Up to 101 amino acids using solid-phase peptide synthesis (SPPS). Standard peptides (≤30 aa) are delivered in approximately 2 weeks. Longer peptides (31–101 aa) may require additional optimization time and are quoted individually based on sequence complexity, hydrophobicity, and required purity.
What purity levels are available?
We offer crude, desalted, and HPLC-purified peptides at >75%, >85%, >95%, and >99% purity. For immunization, ≥85% is typically sufficient. For quantitative assays (ELISA standards, SPR), ≥95% is recommended. For structural studies (NMR, X-ray), >99% is available.
Can you synthesize modified peptides for PTM antibody production?
Yes — this is one of our core strengths. We synthesize both the modified peptide (phospho/methyl/acetyl/crotonyl) for immunization and the unmodified counterpart for negative selection during antibody purification. This two-peptide approach is essential for generating PTM-specific antibodies that do not cross-react with the unmodified form. The peptides integrate directly into our Anti-PTM antibody production pipeline.
What carrier proteins are available for conjugation?
KLH (Keyhole Limpet Hemocyanin) is the default for immunization antigens due to its high immunogenicity. BSA (Bovine Serum Albumin) is used for ELISA coating conjugates. OVA (Ovalbumin) serves as an alternative carrier when BSA cross-reactivity is a concern. Custom carrier proteins are available upon request. All conjugations use optimized crosslinking chemistry with QC verification.
Synthesis feasibility depends on sequence complexity, hydrophobicity, and required modifications. Difficult sequences (multiple Cys, poly-Arg/Lys, highly hydrophobic stretches) may require optimization. Quote-based pricing.
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