AtaGenix Laboratories

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Anti-ldiotype

Anti-idiotype antibodies (Anti-ID Abs) specifically target the unique variable region of antibody drugs, making them essential in pharmacokinetic (PK) and pharmacodynamic (PD) studies. They are widely used as standards for anti-drug antibody (ADA) and neutralizing antibody (NAb) testing, playing a critical role in biopharmaceutical research.

AtaGenix specializes in customized Anti-ID Ab development, offering solutions for PK assays, ADA analysis, and ELISA kit production. With 13+ years of experience and advanced platforms, we provide high-purity antibodies with <5% cross-reactivity, tailored to accelerate your drug development. Partner with AtaGenix for trusted Anti-ID Ab solutions!

 

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AtaGenix utilizes advanced methodologies for anti-idiotype antibody development, including antigen preparation, immunization, hybridoma screening, and antibody purification. Our platforms support rabbit polyclonal, mouse/rabbit monoclonal, and phage display technologies, ensuring flexibility and precision. Each step is optimized to deliver high-purity antibodies with low cross-reactivity, tailored to meet PK, ADA, and NAb assay requirements. Let AtaGenix's expertise streamline your drug development process.

Types of Anti-idiotype Antibodies

Type 1. Antigen-blocking 2. Non-blocking 3. Complex-specific
Schematic Diagram Antigen-blocking Non-blocking Complex-specific
Feature Paratope-specific Not Paratope-specific Partially paratope-specific
Antigen Binding Inhibitory Not inhibitory Not inhibitory
Application Detect free drug only Detect total drug (free and bound) Detect bound drug typically
Selection Guideline Used to detect free antibody drugs for cell-bound targets (e.g., PD1/PDL1). Measures total drug levels (free and bound forms). Detects complexed antibody-drug interactions.

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