Naïve Library Panning

Step 1: Incubation with phage library
Step 2: Wash away non-binders
Step 3: Elution of binders
Step 4: 3 to 5 rounds of panning/biopanning process
Step 5: ELISA to determine specificity of binding

AtaGenix’s naïve library technology enables rapid antibody discovery with high diversity (up to 10¹⁰ variants) while eliminating the need for animal immunization. Compared to hybridoma technology, our phage display approach reduces turnaround time to 3-4 months and removes the need for further humanization, ensuring efficient and cost-effective therapeutic antibody development.

Rapid Antibody Screening

Select high-affinity antibodies within 3-4 months, twice as fast
Animal-Free & Ethical

No animal immunization, fully human naïve library screening
No Further Humanization Needed

Direct selection of fully human antibodies, reducing costs

Available Naïve Libraries at AtaGenix

Library	Format	Species	Size（Capacity）
LiAb-SFCOVID-19™	scFv	Human – COVID-19 recovered donors	1.35 × 10¹⁰
LiAb-SFMAX™	scFv	Human – 5 ethnic groups, 368 donors	7.38 × 10¹⁰
LiAb-SFAutoimmune™	scFv	Human – with autoimmune disease	4.78 × 10⁹
LiAb-VHHMAX™	VHH	Camel, llama, alpaca ， 76 donors	2.71 × 10¹⁰
LiAb-SFDab™	scFv	Dog – 6 breeds，26 donors	1.52 × 10¹⁰
LiAb-SFCab™	scFv	Cat – 10 breeds，78 donors	1.67 × 10¹⁰
LiAb-SFRab™	scFv	Rabbit– 5 breeds，64 donors	2.95 × 10¹⁰
LiPep-12	Peptide 12-mer	/	1.00 × 10⁹
LiPep-7	Peptide 7-mer	/	1.00 × 10⁹