Antibody Discovery

AtaGenix's Antibody Discovery Platform provides end-to-end custom antibody development from antigen to validated monoclonal antibody. With 3 core discovery engines (phage display, hybridoma, single B cell), 9+ specialized service types, and integrated downstream engineering (humanization, affinity maturation, bispecific design), we cover the full spectrum of antibody development needs for research, diagnostics, and therapeutic programs.

Core Discovery Engines

95.4%

Hybridoma Success Rate

10¹¹

Phage Library Diversity

400+

Publications Citing AtaGenix

Choose by Discovery Method

Not sure which platform is right for your project? Use this table to match your requirements to the best discovery route.

Service	Best For	Species	Timeline
Rabbit Single B Cell	Highest affinity (10–100x vs mouse); PTMs, small molecules, easy humanization	Rabbit	16–20 wks
Rapid Hybridoma	Traditional mouse mAb with hybridoma cell line; 95.4% success rate; broad application validation	Mouse	4–6 months
Phage Display	Fully human Abs without immunization; 10¹¹ library diversity; scFv/Fab/VHH formats	Human, camelid, multi-species	2–14 wks
Naïve Library Panning	9 pre-built libraries (human, VHH, rabbit, dog, cat); fastest path; no immunization	Multi-species	2–3 wks (hits)
Immune Library Construction	Custom library from immunized donors; high target-specific affinity; any species	Rabbit, mouse, alpaca, llama, sheep	7–10 wks (build)
Polyclonal Antibody	Multi-epitope recognition; fast turnaround; rabbit, mouse, rat, guinea pig, sheep, chicken (IgY)	6 species	6–8 wks
Bispecific Antibody	KIH, CrossMab, BiTE, tandem scFv, bi-Nanobody; dual-target engagement	N/A (from sequences)	~5 wks
Peptide Synthesis	Custom immunogen prep; up to 101 aa; phospho/methyl/acetyl modifications; KLH/BSA conjugation	N/A	~2 wks

Choose by Application

If your project has a specific functional requirement, these specialized services add targeted screening beyond standard binding ELISA.

Service	Description	Key Differentiator
Anti-Small Molecule	Hapten modification, carrier conjugation, antibody production for food safety, drug screening, biomarkers	Free antigen assessment; hapten-specific affinity purification; 30+ drugs covered in abinScience catalog
Anti-PTM	Phospho, methyl, acetyl, glyco, succinyl, lactyl — modification-specific antibodies with two-round purification	Free antigen design; modified + unmodified peptide pair; guaranteed specificity for modified form only
Anti-Idiotype	Neutralizing, non-neutralizing, drug-target complex Anti-ID Abs for PK/ADA/NAb assays	Guaranteed sandwich ELISA pairs; 120+ catalog Anti-ID products on abinScience; 196 PK ELISA kits
Neutralizing / Blocking	Antibodies with confirmed functional activity: virus neutralization, receptor blocking, toxin inhibition	Functional screening (competitive ELISA, cell-based neutralization) + IC50 potency characterization included

Not Sure Where to Start?

I need the fastest antibody possible

→ Naïve Library Panning — hits in 2–3 weeks from 9 pre-built libraries (human, VHH, rabbit, dog, cat), no immunization needed.

I need a fully human therapeutic antibody

→ Phage Display with LiAb-SFMAX™ human library (7.38 × 10¹⁰ diversity). No humanization step needed.

I need highest-affinity rabbit mAb

→ Rabbit Single B Cell (Xten™ Mab) — 10–100x higher affinity than mouse, ideal for PTMs and difficult antigens.

I need a traditional mouse mAb with cell line

→ Rapid Hybridoma — 95.4% success rate, hybridoma cell line delivered, IHC/IF/FC application-grade screening available.

I need PK/ADA bioanalytical reagents

→ Anti-Idiotype + abinScience catalog — 120+ Anti-ID products, 196 PK ELISA kits, 28 NAb kits off the shelf.

I need a VHH nanobody

→ Naïve VHH Library (LiAb-VHHMAX™, 2.71 × 10¹⁰) for speed, or Immune Library from immunized camelids for highest affinity.