End-to-End BsAb Solutions
Format Strategy & Design
- ■IgG-like, tandem scFv, DVD-Ig™, knob-into-hole / CrossMab
- ■Fc engineering for PK and effector function
- ■Codon-optimized gene synthesis
- ■In-silico liability & developability screening
- ■IP-aware design routes
Engineer, Expression & Purification
- ■CHO/HEK transient & stable cell lines
- ■High-titer upstream process optimization
- ■Site-specific conjugation-ready (ADC/BsADC)
- ■Affinity & multi-step polishing workflows
- ■HCP/DNA/Endotoxin QC panel
Potency & Developability
- ■ELISA, KD by SPR/Biacore & epitope binning
- ■SEC-HPLC aggregation & purity profiles
- ■DSC thermostability & stress study
- ■Cell-based functional readouts
- ■Formulation pre-screen
*Subject to format complexity and project scope.
Service Packages
| Package | Timeline | Deliverables |
|---|---|---|
| Discovery Starter | 2–3 weeks | Design report, sequences, in-silico risk map |
| Express & Characterize | 4–6 weeks | Purified BsAb, SEC/DSC/SPR data, batch report |
One-Stop from Idea to IND-Enabling Data: Transferable upstream parameters (HC/LC ratio, media/feed), and BsADC-ready options (site-specific conjugation, linker/payload guidance).
Why Choose AtaGenix
Format Depth
Experienced across IgG-like, CrossMab, KIH, tandem scFv, DVD-Ig™ with Fc engineering to balance potency and PK.
Speed & Yield
Optimized CHO/HEK routes and upstream parameters deliver rapid material with consistent quality and scalability.
Analytics That De-Risk
Integrated SEC-HPLC, DSC, SPR/Biacore plus optional cell-based assays for decision-ready data packages.
FAQ
Which bispecific formats do you support?
IgG-like (knob-into-hole, CrossMab), tandem scFv, DVD-Ig™ and custom architectures with Fc engineering.
How fast can I receive purified BsAb material?
Our record is 8 weeks from sequence to milligram-scale purified BsAb, subject to format complexity and agreed scope.
What analytics are included?
SEC-HPLC, DSC, ELISA/SPR (KD), and optional cell-based potency assays with a consolidated batch report.
Ready to Start Your BsAb Program?
Tell us your targets and preferred format. Our team will propose a format strategy and timeline tailored to your goals.
