Endo S

ATE00017

Endo S (Endoglycosidase S)

Highly Specific IgG Deglycosylation Enzyme | Recombinant, E. coli-expressed

Product Description

Endo S (Endoglycosidase S), derived from Streptococcus pyogenes, is a highly specific endoglycosidase that cleaves N-linked glycans from the chitobiose core of wild-type IgG heavy chains. It provides precise and efficient enzymatic activity for glycoprotein analysis, immunology research, and biopharmaceutical development.

Product Advantages

High Specificity Precisely removes N-linked glycans at the chitobiose core of IgG heavy chains, avoiding nonspecific reactions.

High Purity & Activity Purity >95% by SDS-PAGE; excellent stability and enzymatic activity; 40,000 U/mL.

No Contaminant Enzymes Free from exoglycosidase and protease contamination, ensuring reliable experimental results.

Convenient Purification N-terminal His tag enables easy removal via affinity chromatography post-reaction.

Applications

IgG Glycan Analysis
Glycoprotein Structural Studies
Biopharmaceutical Development
Immunology & Molecular Biology

Product Specifications

Attribute	Details
Product Name	Endo S (Endoglycosidase S)
Catalog Number	ATE00017
Host	E. coli
Tag	N-terminal His Tag
Cleavage Site	N-linked glycans at the chitobiose core of wild-type IgG heavy chains
Form	Liquid
Buffer	PBS (pH 7.4), 50% glycerol
Purity	>95% (by SDS-PAGE)
Specific Activity	40,000 U/mL
Unit Definition	One unit removes 95% of N-linked glycans from 5 μg native mouse IgG in 10 μL at 37°C for 1 hour
Storage	-20°C; shelf life 12 months
Shipping	Blue ice