产品名称(Product name)
Anti 2019-nCoV Spike glycoprotein monoclonal antibody
描述(description)
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant SARS-CoV-2(2019-nCoV) Spike glycoprotein.
Accession #
P0DTC2
别名(Alternative names)
Spike glycoprotein,S glycoprotei,E2,Peplomer protein,Spike protein S1,Spike protein S2,Spike protein S2',S
稳定性&储存(Stability &Storage)
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
特异性(Spcificty)
Recognizes SARS-CoV-2 Spike glycoprotein
亚型(Isotype)
IgG 1
宿主(Host)
Mouse
克隆性(Clonality)
Monoclonal
克隆号(Clone No.)
19-J-16
偶连物(Conjugation)
Unconjugated
种属反应性(Species reactivity)
Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) (SARS-CoV-2)
应用实验(Tested applications)
WB
免疫原(Immunogen)
Recombinant SARS-CoV-2 (2019-nCoV) Spike protein fragment 1[679-833]
Mediates fusion of the virion and cellular membranes by acting as a class I viral fusion protein. Under the current model, the protein has at least three conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.
状态(Form)
Liquid
储存溶液(Buffer)
PBS, pH7.4, containing 0.05% proclin300, 50% glycerol.
浓度(Concentration)
0.42mg/ml
分子量(MW)
142kDa
应用实验及稀释比例(Dilution Range)
WB:1:1000~4000
For research use only .Not for use in clinical diagnostic procedures.