产品名称(Product name)
Anti ACE2 polyclonal antibody
货号(Catalog#)
ATP239
描述(description)
Produced in rabbits immunized with purified,Recombinant Human ACE-2 protein
Accession #
Q9BYF1
别名(Alternative names)
Angiotensin-converting enzyme 2,Angiotensin-converting enzyme homolog,ACEH,Angiotensin-converting enzyme-related carboxypeptidase,ACE-related carboxypeptidase,Metalloprotease MPROT15,Processed angiotensin-converting enzyme 2
稳定性&储存(Stability &Storage)
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -84 °C for twelve months from the date of receipt.
特异性(Spcificty)
Recognizes Human ACE-2 protein
亚型(Isotype)
IgG
宿主(Host)
Rabbit
克隆性(Clonality)
Polyclonal
偶连物(Conjugation)
Unconjugate
种属反应性(Species reactivity)
Homo sapiens (Human)
应用实验(Tested applications)
Elisa,WB
免疫原(Immunogen)
Recombinant Human ACE-2 protein(Leu392-Ser740)
Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor don’t inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function.
状态(Form)
Liquid
储存溶液(Buffer)
PBS, pH7.4, containing 0.05% proclin300, 50% glycerol.
浓度(Concentration)
0.96mg/ml
分子量(MW)
92kDa
应用实验及稀释比例(Dilution Range)
Elisa:1:4000~1:8000;WB:1:1000~1:5000