普健生物(武汉)科技有限公司(AtaGenix)

Anti S100B mouse monoclonal antibody

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ATMA10112Mo
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产品名(Product Name)icon
Anti S100B mouse monoclonal antibody
货号(Catalog No.)icon
ATMA10112Mo
种类(Category)icon
Primary antibody
宿主(Host)icon
Mouse
反应种属(Species specificity)icon
Homo sapiens (Human)
克隆性(Clonality)icon
Monoclonal
克隆编号(Clone No.)icon
2D10
偶连物(Conjugation)icon
Unconjugated
免疫原(Immunogen)icon
Recombinant protein of human S100B
别名icon
S100B,Protein S100-B,S-100 protein beta chain,S-100 protein subunit beta,S100 calcium-binding protein B
Uniprot IDicon
P04271
状态(Form)icon
Liquid
储存溶液(Buffer)icon
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
存放条件(Storage)icon
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 4 °C for frequent use.
Store at -20 to -80 °C for twelve months from the date of receipt.
浓度(Concentration)icon
0.5mg/ml
亚型(Isotype)icon
IgG2b
分子量(MW)icon
11kDa
纯化方式(Purity)icon
Protein G purified from mice ascites
/
S100B is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs and has been implicated in the regulation of cellular activities such as metabolism, motility and proliferation. In the nervous system, S100B is constitutively released by astrocytes into the extracellular space and at nanomolar concentrations, it can promote neurite outgrowth and protect neurons against oxidative stress. Within the central nervous system (CNS), S100B is thought to be a marker for astroglial activation, linking astrocyte dysfunction to schizophrenia. In addition to astrocytes, S100B is released from many cell types, such as, adipocytes, chondrocytes, cardiomyocytes and lymphocytes. Serum S100B represents a new bomarker for mood disorders.

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