普健生物(武汉)科技有限公司(AtaGenix)

Anti S100β mouse monoclonal antibody

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ATMA10061Mo
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产品名(Product Name)icon
Anti S100β mouse monoclonal antibody
货号(Catalog No.)icon
ATMA10061Mo
种类(Category)icon
Primary antibody
宿主(Host)icon
Mouse
反应种属(Species specificity)icon
Homo sapiens (Human)
应用实验(Tested applications)icon
Elisa,IHC
克隆性(Clonality)icon
Monoclonal
克隆编号(Clone No.)icon
148-C-11
偶连物(Conjugation)icon
Unconjugate
免疫原(Immunogen)icon
Recombinant protein of full length of human S100β
别名icon
S-100 protein beta chain;S100 calcium-binding protein B
Uniprot IDicon
P04271
状态(Form)icon
Liquid
储存溶液(Buffer)icon
PBS, pH7.4, containing 0.05% proclin300, 50% glycerol.
存放条件(Storage)icon
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 4 °C for frequent use.
Store at -20 to -80 °C for twelve months from the date of receipt.
浓度(Concentration)icon
0.33mg/ml
亚型(Isotype)icon
IgG1
分子量(MW)icon
11 kDa
纯化方式(Purity)icon
Protein G purified from mice ascites
Elisa:1:1000~5000,IHC:1:50~100
PMID: 20351179,PMID: 22399290,PMID: 9925766,PMID: 9925766,PMID: 4031854,PMID: 9925766,PMID: 20943659
Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity

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