产品名称(Product name)
Anti CD147 polyclonal antibody
描述(description)
Produced in rabbits immunized with purified,Recombinant Human CD147 protein
Accession #
P35613-2
别名(Alternative names)
Collagenase stimulatory factor,OK blood group antigen,Leukocyte activation antigen M6,Tumor cell-derived collagenase stimulatory factor,Basigin,Extracellular matrix metalloproteinase inducer,CD147,TCSF,EMMPRIN,5F7,BSG
稳定性&储存(Stability &Storage)
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
特异性(Spcificty)
Recognizes Human CD147 protein
亚型(Isotype)
IgG
宿主(Host)
Rabbit
克隆性(Clonality)
Polyclonal
偶连物(Conjugation)
Unconjugated
种属反应性(Species reactivity)
Human
应用实验(Tested applications)
WB,ICC,IHC
免疫原(Immunogen)
Recombinant protein of human CD147(Ala22-Ala207).
BSG, also named as 5F7, Basigin, EMMPRIN, TCSF and CD147, plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. It stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS).CD147 may target monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to plasma membranes of retinal pigment epithelium and neural retina. It seems to be a receptor for oligomannosidic glycans. CD147 is a receptor of CypA, inducing matrix metalloproteinase expression and mediating the degradation of the extracellular matrix, plays an important role in tumorigenesis and invasion in oral cancer. It has been considered as an objective and effective marker to predict invasion and prognosis in various cancers.
状态(Form)
Liquid
储存溶液(Buffer)
PBS,pH7.4,containing 0.05% proclin300,50% glycerol.
浓度(Concentration)
0.48mg/ml
分子量(MW)
42kDa
应用实验及稀释比例(Dilution Range)
WB:1:2000~1:8000,ICC:1:50~200,IHC:1:50~100