产品名称(Product name)
Recombinant Human SR-B1 protein
货号(Catalog#)
ATAP10734
描述(description)
Recombinant Human SR-B1 is produced by Mammalian cells expression system and the target gene encoding Pro33-Tyr443 is expressed with His Tag
表达系统(Expression system)
Mammalian cells
种属(Species)
Homo sapiens (Human)
Accession #
Q8WTV0
别名(Alternative names)
SCARB1,CD36L1,SRB1,CLA-1,SR-BI,HDLQTL6
预测分子量(Predicted Molecular Mass)
46.67kDa
纯度(Purity)
>90% as determined by SDS-PAGE
内毒素(Endotoxin level)
Please contact with the lab for this information
制剂(Formulation)
Supplied as solution form in PBS, pH7.5 or lyophilized from PBS, pH7.5
运输方式(Shipping)
In general, proteins are shipped out with blue ice unless customers require otherwise.
稳定性&储存(Stability &Storage)
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
复溶(Reconstitution)
Please refer to the instraction in the hard copy of COA.
应用(Application)
Immunogen
Scavenger receptor class B member 1 (SRB1) is also known as SR-BI, CD36 and LIMPII analogous 1 (CD36L1), CLA-1, is a member of the scavenger receptor family or CD36 family. CD36L1 is an integral membrane protein found in numerous cell types/tissues, including the liver and adrenal. SRB1 is receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. CLA-1 facilitates the flux of free and esterified cholesterol between the cell surface and extracellular donors and acceptors, such as high-density lipoprotein (HDL) and to a lesser extent, apoB-containing lipoproteins and modified lipoproteins. SCARB1 is, along with CD81, the receptor for the entry of the Hepatitis C virus glycoprotein E2 in liver cells, and binding between SCARB1 and E2 was found to be independent of the genotype of the viral isolate. SRB1 plays an important role in the uptake of HDL cholesteryl ester.