产品名称(Product name)
Recombinant Human TMPRSS2 protein
货号(Catalog#)
ATAP00900
描述(description)
Recombinant Human TMPRSS2 is produced by E.coli expression system and the target gene encoding Ser284-Gly492 is expressed with His Tag
表达系统(Expression system)
E.coli
种属(Species)
Homo sapiens (Human)
Accession #
O15393
别名(Alternative names)
Transmembrane protease serine 2,Serine protease 10.
预测分子量(Predicted Molecular Mass)
25.65 kDa
纯度(Purity)
>90% as determined by SDS-PAGE
内毒素(Endotoxin level)
Please contact with the lab for this information
制剂(Formulation)
Supplied as solution form in PBS, pH7.5 or lyophilized from PBS, pH7.5
运输方式(Shipping)
In general, proteins are shipped out with blue ice unless customers require otherwise.
稳定性&储存(Stability &Storage)
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
复溶(Reconstitution)
Please refer to the instraction in the hard copy of COA.
应用(Application)
Immunogen
Plasma membrane-anchored serine protease that participates in proteolytic cascades of relevance for the normal physiologic function of the prostate. Androgen-induced TMPRSS2 activates several substrates that include pro-hepatocyte growth factor/HGF, the protease activated receptor-2/F2RL1 or matriptase/ST14 leading to extracellular matrix disruption and metastasis of prostate cancer cells. In addition, activates trigeminal neurons and contribute to both spontaneous pain and mechanical allodynia.