产品名称(Product name)
Anti 2019-nCoV E protein polyclonal antibody
描述(description)
Produced in rabbits immunized with purified,Recombinant SARS-CoV-2 E protein
Accession #
P0DTC4
别名(Alternative names)
2019-nCoV E protein,2019-nCoV sM protein,Envelope small membrane protein
稳定性&储存(Stability &Storage)
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -99 °C for twelve months from the date of receipt.
特异性(Spcificty)
Recognizes SARS-CoV-2 E protein
亚型(Isotype)
IgG
宿主(Host)
Rabbit
克隆性(Clonality)
Polyclonal
偶连物(Conjugation)
Unconjugate
种属反应性(Species reactivity)
Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) (SARS-CoV-2)
应用实验(Tested applications)
Elisa,WB
免疫原(Immunogen)
Recombinant SARS-CoV-2 E protein(Met1-Val75)
Coronavirus envelope (E) proteins are short (100 residues) polypeptides that contain at least one transmembrane (TM) domain and a cluster of 2-3 juxtamembrane cysteines. These proteins are involved in viral morphogenesis and tropism, and their absence leads in some cases to aberrant virions, or to viral attenuation. In common to other viroporins, coronavirus envelope proteins increase membrane permeability to ions, plays a central role in virus morphogenesis and assembly. Acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport. Also plays a role in the induction of apoptosis. Activates the host NLRP3 inflammasome, leading to IL-1beta overproduction.
状态(Form)
Liquid
储存溶液(Buffer)
PBS, pH7.4, containing 0.05% proclin300, 50% glycerol.
浓度(Concentration)
0.71 mg/ml
分子量(MW)
8kDa
应用实验及稀释比例(Dilution Range)
Elisa:1:4000~1:8000,WB:1:1000~5000