产品名称(Product name)
Anti 2019-nCoV S1 Protein polyclonal antibody
货号(Catalog#)
ATP246
描述(description)
Produced in rat immunized with purified,Recombinant SARS-CoV-2 S1 Protein
Accession #
P0DTC2
别名(Alternative names)
Spike glycoprotein,E2,Peplomer protein,Spike protein S1,S
稳定性&储存(Stability &Storage)
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -91 °C for twelve months from the date of receipt.
特异性(Spcificty)
Recognizes SARS-CoV-2 S1 Protein
亚型(Isotype)
IgG
宿主(Host)
Rat
克隆性(Clonality)
Polyclonal
偶连物(Conjugation)
Unconjugate
种属反应性(Species reactivity)
Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) (SARS-CoV-2)
应用实验(Tested applications)
Elisa
免疫原(Immunogen)
Recombinant SARS-CoV-2 S1 Protein(Val16-Gln677)
Attaches the virion to the cell membrane by interacting with host receptor, initiating the infection. Binding to human ACE2 receptor and internalization of the virus into the endosomes of the host cell induces conformational changes in the Spike glycoprotein. Uses also human TMPRSS2 for priming in human lung cells which is an essential step for viral entry. Can be alternatively processed by host furin . Proteolysis by cathepsin CTSL may unmask the fusion peptide of S2 and activate membranes fusion within endosomes.
状态(Form)
Liquid
储存溶液(Buffer)
PBS, pH7.4, containing 0.05% proclin300, 50% glycerol.
浓度(Concentration)
0.61mg/ml
分子量(MW)
141kDa
应用实验及稀释比例(Dilution Range)
Elisa:1:4000~1:8000