产品名称(Product name)
Anti 2019-nCoV NSP3 polyclonal antibody
货号(Catalog#)
ATP235
描述(description)
Produced in rabbits immunized with purified,Recombinant SARS-CoV-2 NSP3 protein
Accession #
P0DTC1
别名(Alternative names)
Non-structural protein 3,PL2-PRO,Papain-like proteinase,PL-PRO,Replicase polyprotein 1a
稳定性&储存(Stability &Storage)
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
特异性(Spcificty)
Recognizes SARS-CoV-2 NSP3 protein
亚型(Isotype)
IgG
宿主(Host)
Rabbit
克隆性(Clonality)
Polyclonal
偶连物(Conjugation)
Unconjugate
种属反应性(Species reactivity)
Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) (SARS-CoV-2)
应用实验(Tested applications)
Elisa;WB
免疫原(Immunogen)
Recombinant SARS-CoV-2 NSP3(Glu1024-Gln1198)
Responsible for the cleavages located at the N-terminus of the replicase polyprotein. In addition, PL-PRO possesses a deubiquitinating/deISGylating activity and processes both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains from cellular substrates. Participates together with nsp4 in the assembly of virally-induced cytoplasmic double-membrane vesicles necessary for viral replication. Antagonizes innate immune induction of type I interferon by blocking the phosphorylation, dimerization and subsequent nuclear translocation of host IRF3. Prevents also host NF-kappa-B signaling.
状态(Form)
Liquid
储存溶液(Buffer)
PBS, pH7.4, containing 0.05% proclin300, 50% glycerol.
浓度(Concentration)
0.33mg/ml
分子量(MW)
200kDa
应用实验及稀释比例(Dilution Range)
Elisa:1:4000~1:8000;
WB:1:1000-2000