产品名称(Product name)
Anti ACE2 mouse monoclonal antibody
货号(Catalog#)
ATMA10198Mo
描述(description)
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human ACE2 protein.
Accession #
Q9BYF1
别名(Alternative names)
Angiotensin-converting enzyme 2 ,Angiotensin-converting enzyme homolog,ACEH,ACE-related carboxypeptidase,Metalloprotease MPROT15
稳定性&储存(Stability &Storage)
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
特异性(Spcificty)
Recognizes Human ACE2 protein
亚型(Isotype)
IgG1
宿主(Host)
Mouse
克隆性(Clonality)
Monoclonal
偶连物(Conjugation)
Unconjugated
种属反应性(Species reactivity)
Homo sapiens (Human)
应用实验(Tested applications)
WB,IHC,Neutralization
免疫原(Immunogen)
Recombinant Human ACE2 protein
Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor don’t inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function.
状态(Form)
Liquid
储存溶液(Buffer)
PBS, pH7.4, containing 0.05% proclin300, 50% glycerol.
浓度(Concentration)
0.62 mg/ml
分子量(MW)
110kDa
应用实验及稀释比例(Dilution Range)
WB:1:1000~4000;IHC:1:50~100,Neutralization:0.25ug/ml-1ug/ml
For research use only .Not for use in clinical diagnostic procedures.