普健生物(武汉)科技有限公司(AtaGenix)

CD38 mouse monoclonal antibody

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ATDA00051
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产品名(Product Name)icon
CD38 mouse monoclonal antibody
货号(Catalog No.)icon
ATDA00051
种类(Category)icon
Primary antibody
宿主(Host)icon
Mouse
反应种属(Species specificity)icon
This antibody detects endogenous levels of human CD38. Heat-induced epitope retrieval (HIER) Citrate buffer of pH6.0 was highly recommended as antigen repair method in paraffin section
应用实验(Tested applications)icon
IHC-p
克隆性(Clonality)icon
Monoclonal
免疫原(Immunogen)icon
Synthesized peptide derived from human CD38.
别名icon
ADP-ribosyl cyclase 1,Cyclic ADP-ribose hydrolase 1,cADPr hydrolase 1,CD antigen CD38
Uniprot IDicon
P28907
体外诊断备案号icon
鄂汉械备20190197号
状态(Form)icon
Liquid
储存溶液(Buffer)icon
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
存放条件(Storage)icon
Stored at -20℃.Avoid repeated freeze-thaw cycles.
浓度(Concentration)icon
1 mg/ml
亚型(Isotype)icon
IgG1,Kappa
IHC-p:1:100-1:500
    CD38 molecule(CD38) Homo sapiens The protein encoded by this gene is a non-lineage-restricted,type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose,an intracellular calcium ion mobilizing messenger.The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein.This protein has an N-terminal cytoplasmic tail,a single membrane-spanning domain,and a C-terminal extracellular region with four N-glycosylation sites.Crystal structure analysis demonstrates that the functional molecule is a dimer,with the central portion containing the catalytic site.It is used as a prognostic marker for patients with chronic lymphocytic leukemia.Alternative splicing results in multiple transcript variants.

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