普健生物(武汉)科技有限公司(AtaGenix)

Adrenocorticotropin (ACTH) mouse monoclonal antibody

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ATDA00008
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产品名(Product Name)icon
Adrenocorticotropin(ACTH) mouse monoclonal antibody
货号(Catalog No.)icon
ATDA00008
种类(Category)icon
Primary antibody
宿主(Host)icon
Mouse
反应种属(Species specificity)icon
This antibody detects endogenous levels of human Adrenocorticotropin(ACTH). Heat-induced epitope retrieval (HIER) TRIS-EDTA of pH8.0 was highly recommended as antigen repair method in paraffin section
应用实验(Tested applications)icon
WB:500-2000; IHC-p:1:100-500
克隆性(Clonality)icon
Monoclonal
免疫原(Immunogen)icon
Synthesized peptide derived from human Adrenocorticotropin(ACTH).
别名icon
Pro-opiomelanocortin (POMC),Corticotropin-lipotropin,Potential peptide,Corticotropin,Adrenocorticotropic hormone(ACTH)
Uniprot IDicon
P01189
状态(Form)icon
Liquid
储存溶液(Buffer)icon
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
存放条件(Storage)icon
Stored at -20℃.Avoid repeated freeze-thaw cycles.
浓度(Concentration)icon
1 mg/ml
亚型(Isotype)icon
IgG1,Kappa
WB:500-2000; IHC-p:1:100-500
    Proopiomelanocortin(POMC) Homo sapiens This gene encodes a preproprotein that undergoes extensive,tissue-specific,post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases.There are eight potential cleavage sites within the preproprotein and,depending on tissue type and the available convertases,processing may yield as many as ten biologically active peptides involved in diverse cellular functions.The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used; adrenocorticotrophin,essential for normal steroidogenesis and the maintenance of normal adrenal weight,and lipotropin beta are the major end products.In other tissues,including the hypothalamus,placenta,and epithelium,all cleavage sites may be used,giving rise to peptides with roles in pain and energy homeostasis,melanocyte stimulation,and immune modulation.

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